Psychologists report an error in the NICE guidelines for autism

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(University of Bath) New research from psychologists at the University of Bath suggests a widely used autism screening approach is being misused.

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Publication date: Available online 8 October 2020Source: Neurología (English Edition)Author(s): C. Peña-Salazar, M. López Cuiña, V. Chavarría, B. Robles Olmo

Source: NeurologiaCategory: Neurology Source Type: research

Campbell

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disruptions in social communication and behavioral flexibility. Both genetic and environmental factors contribute to ASD risk. Epidemiologic studies indicate that roadway vehicle exhaust and in utero exposure to diesel particulate matter (DPM) are associated with ASD. Using the Comparative Toxicogenomics Database (CTD), we identified genes connected to DPM exposure and ASD, extracted the known enhancers/promoters of the identified genes, and integrated this with Assay for Transposase Accessible Chromatin (ATAC-seq) data from DPM…

Publication date: Available online 8 October 2020Source: Stem Cell ResearchAuthor(s): Morad Kamand, Mirolyuba Ilieva, Sheena Louise Forsberg, Mads Thomassen, Åsa Fex Svenningsen, Morten Meyer, Tanja Maria Michel

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition with hallmark behavioral manifestations including impaired social communication and restricted repetitive behavior. In addition, many affected individuals display metabolic imbalances, immune dysregulation, gastrointestinal (GI) dysfunction, and altered gut microbiome compositions.

Source: Biological PsychiatryCategory: Psychiatry Authors: Tags: Archival Report Source Type: research

(Mary Ann Liebert, Inc./Genetic Engineering News) Ableist language is often used by autism researchers, which assumes that autistic people are ” broken ” or inferior to non-autistic people.

Abstract
BACKGROUND: Alexithymia (difficulties in identifying and describing emotion) is a transdiagnostic trait implicated in social-emotional and mental health problems in the general population. Many autistic individuals experience significant social-communication difficulties and elevated anxiety/depression and alexithymia. Nevertheless, the role of alexithymia in explaining individual variability in the quality/severity of social-communication difficulties and/or anxiety and depression symptoms in autism remains poorly understood.
METHODS: In total, 337 adolescents and adults (autism N = 179) were assess…

Source: Psychological MedicineCategory: Psychiatry Authors: Tags: Psychol Med Source Type: research

ConclusionsDisrupted protein interactions identify gene sets involved in risk for ASD. Their gene expression during brain development and within cell types highlights how they relate to ASD.

Source: Molecular AutismCategory: Molecular Biology Source Type: research

Although fMRI studies have produced considerable evidence for differences in the spatial connectivity of resting-state brain networks in persons with autism spectrum disorder (ASD) relative to typically developing (TD) peers, little is known about the temporal dynamics of these brain networks in ASD. The aim of this study was to examine the EEG microstate architecture in children with ASD as compared to TD at rest in two separate conditions – eyes-closed (EC) and eyes-open (EO). EEG microstate analysis was performed on resting-state data of 13 ASD and 13 TD children matched on age, gender, and IQ. We found that child…

Individuals with autism spectrum disorders (ASD) are impaired not only in social competencies but also in sensory perception, particularly olfaction. The olfactory ability of individuals with ASD has been examined in several psychophysical studies, but the results have been highly variable, which might be primarily due to methodological difficulties in the control of odor stimuli (e.g., the problem of lingering scents). In addition, the neural correlates of olfactory specificities in individuals with ASD remain largely unknown. To date, only one study has investigated this issue using functional magnetic resonance imaging …

Victoria Rodr íguez-Roldán, The Intersection between Disability and LGBT Discrimination and Marginalization, 28 (3) Am. U. J. Gender 2 (2020): In February of 2016, Kayden Clarke, a 24-year old autistic, transgender man in Mesa, Arizona, allegedly experienced a suicidal crisis. As…

Source: HealthLawProf BlogCategory: Medical Law Authors: Source Type: blogs

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